The unixODBC Project goals are to develop and promote unixODBC to be the definitive standard for ODBC on non MS Windows platforms. This is to include GUI support for both KDE and GNOME.

See http://www.unixodbc.org/

OpenOffice

Actually, OpenOffice.org already allows to access databases using UnixODBC - just choose "ODBC" as Connection Type in the data source administration dialog (or, if you're using a recent developer snapshot, use Edit > Properties > Database in the menu.